The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 24, 2018

Filed:

May. 13, 2016
Applicant:

Erytech Pharma, Lyons, FR;

Inventors:

Yann Godfrin, Lyons, FR;

Alice Banz, Lyons, FR;

Assignee:

ERYTECH PHARMA, Lyons, FR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/28 (2015.01); A61K 35/26 (2015.01); C12N 5/00 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); A61K 35/18 (2015.01); A61K 47/02 (2006.01); A61K 47/22 (2006.01); A61K 47/26 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); A61K 35/18 (2013.01); A61K 47/02 (2013.01); A61K 47/22 (2013.01); A61K 47/26 (2013.01); C07K 16/2806 (2013.01); A61K 2039/5154 (2013.01); A61K 2039/5156 (2013.01); A61K 2039/55522 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/572 (2013.01); A61K 2039/6056 (2013.01);
Abstract

The invention relates to a composition which induces, in a host, a cytotoxic cell response directed against cells expressing an antigen, in particular tumor cells, and which comprises red blood cells containing said antigen. These red blood cells may be in the form of an immune complex with an immunoglobulin, in particular IgG, which recognizes an epitope at the surface of the red blood cells, and/or be heat-treated or chemically treated so as to promote phagocytosis of said red blood cells by dendritic cells. As a variant, the red blood cells may be xenogenic red blood cells. The invention also relates to a therapeutic especially anti-tumor vaccine containing such a composition.


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