The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 24, 2018
Filed:
Dec. 01, 2015
Cornell Research Foundation, Inc., Ithaca, NY (US);
Hazel H. Szeto, New York, NY (US);
CORNELL RESEARCH FOUNDATION, INC., Ithaca, NY (US);
Abstract
The invention provides a method for reducing oxidative damage in a mammal, a removed organ, or a cell in need thereof. The method comprises administering an effective amount of an aromatic cationic peptide. The aromatic cationic peptide has (a) at least one net positive charge; (b) a minimum of three amino acids; (c) a maximum of about twenty amino acids, (d) a relationship between the minimum number of net positive charges (p) and the total number of amino acid residues (r) wherein 3 pis the largest number that is less than or equal to r+1; (e) a relationship between the minimum number of aromatic groups (a) and the total number of net positive charges (p) wherein 3a or 2a is the largest number that is less than or equal to p+1, except that when a is 1, pmay also be 1; and (f) at least one tyrosine or tryptophan amino acid.