The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 24, 2018
Filed:
Nov. 06, 2014
Applicant:
Aeromics, Inc., Cleveland, OH (US);
Inventors:
Marc F. Pelletier, Shaker Heights, OH (US);
Paul Robert McGuirk, Spring Hill, FL (US);
George William Farr, Rocky River, OH (US);
Steven Williams, Columbus, OH (US);
Assignee:
AEROMICS, INC., Cleveland, OH (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/661 (2006.01); A61K 31/167 (2006.01); C07F 9/09 (2006.01); A61K 9/00 (2006.01); A61K 47/18 (2017.01); A61K 31/222 (2006.01); A61K 31/5375 (2006.01);
U.S. Cl.
CPC ...
A61K 31/661 (2013.01); A61K 9/0019 (2013.01); A61K 31/167 (2013.01); A61K 31/222 (2013.01); A61K 31/5375 (2013.01); A61K 47/18 (2013.01); A61K 47/186 (2013.01); C07F 9/09 (2013.01);
Abstract
The present invention relates to the use of selective aquaporin inhibitors, e.g., of aquaporin-4 or aquaporin-2, e.g., certain phenylbenzamide compounds, for the prophylaxis, treatment and control of aquaporin-mediated conditions, e.g., glioblastoma and ovarian hyperstimulation syndrome. The invention provides, inter alia, methods of treating or controlling a disease condition mediated by an aquaporin, e.g., diseases or conditions of water imbalance and other diseases.