The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 2018
Filed:
Feb. 17, 2015
Shimadzu Corporation, Kyoto-shi, Kyoto, JP;
Hidenori Takahashi, Kyoto, JP;
Kei Kodera, Kyoto, JP;
Sadanori Sekiya, Kusatsu, JP;
Kenichi Taniguchi, Kyoto, JP;
SHIMADZU CORPORATION, Kyoto-shi, JP;
Abstract
A cloud of ions captured in an ion trap () is irradiated with a stream of hydrogen radicals cast through a radical particle introduction hole () bored in a ring electrode () at a flow rate of 4×10[atoms/s]. As a result, a radical induced dissociation which does not rely on the transfer or capture of electrons occurs within the ion trap (), whereby c/z-type fragment ions are efficiently generated. After the irradiation with the hydrogen radicals, a supplemental collision-induced dissociation process may performed by introducing inert gas into the ion trap () and resonantly exciting the ions, in order to further promote the generation of the c/z-type fragment ions. In this manner, according to the present invention, it is possible to achieve radical induced dissociation of singly-charged ions derived from a peptide and use the thereby generated c/z-type fragment ions for mass spectrometry.