The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 2018
Filed:
Feb. 05, 2016
Life Technologies Corporation, Carlsbad, CA (US);
Yong Chu, Castro Valley, CA (US);
Life Technologies Corporation, Carlsbad, CA (US);
Abstract
The present teachings relate to a method and system for determining Regions of Interest (ROI) for one or more biological samples in a laboratory instrument. The method can include an optical system capable of imaging florescence emission from a plurality of sample wells. An initial ROI, its center location and size can be estimated from the fluorescence detected from each well. From this information the average size of the ROIs can be determined and global gridding models can be derived to better locate each of the ROIs. The global gridding models can then be applied to the ROIs to improve the precision of the ROI center locations. Sample wells not originally providing fluorescence ROIs can be recovered through the use of mapping functions. The radius of each ROI can then be adjusted to improve the signal-to-noise ratio of the optical system.