The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 17, 2018

Filed:

Sep. 06, 2016
Applicant:

Hadasit Medical Research Services and Development Ltd., Jerusalem, IL;

Inventor:

Rifaat Safadi, Nazareth Elit, IL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C12Q 1/68 (2018.01); A61K 31/7088 (2006.01); A61K 45/06 (2006.01); C12N 15/113 (2010.01); A61K 31/713 (2006.01); A61K 31/7105 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); A61K 45/06 (2013.01); C12N 15/1138 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); C12Q 2600/158 (2013.01);
Abstract

The present invention provides a method of diagnosing and/or monitoring a liver disorder in a subject. The method calls for isolating an immune cell population from a biological sample of the subject; and detecting expression level of an NLGn4 gene product in the immune cell population using NLGn4 specific primers or NLGn4 specific probes.


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