The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 2018
Filed:
Jun. 17, 2014
Applicants:
Institute of Zoology, Chinese Academy of Sciences, Beijing, CN;
Emory University School of Medicine, Atlanta, GA (US);
Inventors:
Dahua Chen, Beijing, CN;
Peng Jin, Atlanta, GA (US);
Qinmiao Sun, Beijing, CN;
Weiqi Tan, Beijing, CN;
Assignees:
Institute of Zoology, Chinese Academy of Sciences, Beijing, CN;
Emory University School of Medicine, Atlanta, GA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/07 (2010.01); C12N 5/074 (2010.01); C12N 15/62 (2006.01); C12N 15/86 (2006.01); C07K 14/47 (2006.01); C12N 7/00 (2006.01); C12Q 1/68 (2018.01);
U.S. Cl.
CPC ...
C12N 5/0696 (2013.01); C07K 14/4702 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); C12Q 1/6881 (2013.01); C07K 2319/71 (2013.01); C12N 2501/602 (2013.01); C12N 2501/603 (2013.01); C12N 2501/604 (2013.01); C12N 2501/605 (2013.01); C12N 2501/606 (2013.01); C12N 2506/02 (2013.01); C12N 2740/10043 (2013.01); C12N 2740/10052 (2013.01); C12N 2740/13043 (2013.01);
Abstract
Provided is a protein coded by a gene related to cell totipotency and a transcriptional activation domain of a mammalian YAP protein or a fusion protein of a segment with a transcriptional control activity, a coding nucleotide sequence, an expression vector and a composition thereof, as well as a method for inducing the pluripotent stem cells by using the fusion protein.