The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 2018
Filed:
Nov. 04, 2013
Applicant:
Fraunhofer-gesellschaft Zur Foerderung Der Angewandten Forschung E.v, Munich, DE;
Inventors:
Stefan Barth, Aachen, DE;
Sonja Schiffer, Juechen, DE;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 15/00 (2006.01); C07K 16/00 (2006.01); C07K 16/28 (2006.01); C12N 9/64 (2006.01); C12N 9/76 (2006.01);
U.S. Cl.
CPC ...
C07K 16/283 (2013.01); C07K 16/2863 (2013.01); C07K 16/2866 (2013.01); C07K 16/2878 (2013.01); C12N 9/6427 (2013.01); C12N 9/6467 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2319/00 (2013.01); C07K 2319/50 (2013.01); C07K 2319/55 (2013.01);
Abstract
The technology provided herein relates to novel immunoproteases suitable to induce apotosis in selected diseased target cells, comprising the serine protease granzyme M, and methods for using such cytolytic fusion proteins for the treatment of various diseases, in particular for the treatment of cancer.