The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 2018
Filed:
Dec. 12, 2014
Rijksuniversiteit Groningen, Groningen, NL;
Academisch Ziekenhuis Groningen, Groningen, NL;
Jan Maarten Van Dijl, Groningen, NL;
Girbe Buist, Groningen, NL;
Hendrik Petrus Jozef Bonarius, Groningen, NL;
Neeltje Margaretha Kooi, Groningen, NL;
Goffe Sytse Elsinga, De Meern, NL;
Herman Groen, Groningen, NL;
Rijksuniversiteit Groningen, Groningen, NL;
Academisch Ziekenhuis Groningen, Groningen, NL;
Abstract
The invention relates to the field of immunology and vaccine development. In particular, it relates to antibodies and fragments thereof againstand to therapeutic and diagnostic uses thereof. Provided is an isolated antibody or a functional fragment thereof, which binds to an epitope of the Immunodominant Staphylococcal antigen A (IsaA), wherein said antibody comprises at least four Isa A epitope-binding CDR sequences selected from the group consisting of SEQ ID NO: 1; SEQ ID NO: 2; SEQ ID NO: 3; SEQ ID NO: 4; SEQ ID NO: 5; SEQ ID NO: 6, and functional equivalents thereof having an amino acid sequence that is at least 85% identical to an amino acid sequence of SEQ ID NO: 1-6.