The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 2018
Filed:
Oct. 21, 2015
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Katherine Young, Metuchen, NJ (US);
David B. Olsen, Landsdale, PA (US);
Sheo B. Singh, Edison, NJ (US);
Jing Su, Scotch Plains, NJ (US);
Robert R. Wilkening, Maplewood, NJ (US);
James M. Apgar, Highland, NJ (US);
Dongfang Meng, Morganville, NJ (US);
Dann Parker, Cranford, NJ (US);
Mihir Mandal, Westfield, NJ (US);
Lihu Yang, Edison, NJ (US);
Ronald E. Painter, Piscataway, NJ (US);
Qun Dang, Westfield, NJ (US);
Takao Suzuki, Shanghai, CN;
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The present invention relates to novel nargenicin related compounds which can inhibit DnaE and have antibacterial, particularly antimycobacterial activity against. The present invention also relates to method for inhibiting growth of mycobacterial cells as well as a method of treating mycobacterial infections byby administering an antimycobacterially effective amount of nargenicin or a nargenicin-related compound and/or their pharmaceutically acceptable salts.