The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 2018
Filed:
Mar. 09, 2016
Applicants:
Incyte Corporation, Wilmington, DE (US);
Incyte Holdings Corporation, Wilmington, DE (US);
Inventors:
Andrew P. Combs, Kennett Square, PA (US);
Richard B. Sparks, Wilmington, DE (US);
Thomas P. Maduskuie, Jr., Wilmington, DE (US);
Assignees:
Incyte Holdings Corporation, Wilmington, DE (US);
Incyte Corporation, Wilmington, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/553 (2006.01); C07D 413/06 (2006.01); C07D 413/14 (2006.01); C07D 487/04 (2006.01); A61K 31/519 (2006.01); C07C 53/18 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/519 (2013.01); A61K 31/553 (2013.01); C07C 53/18 (2013.01);
Abstract
The present invention provides bicyclic azaheterocyclobenzylamines of Formula I: wherein the variables are defined herein, that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases.