The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 17, 2018

Filed:

Dec. 03, 2015
Applicant:

Concert Pharmaceuticals, Inc., Lexington, MA (US);

Inventors:

Julie F. Liu, Lexington, MA (US);

Scott L. Harbeson, Cambridge, MA (US);

Roger D. Tung, Lexington, MA (US);

Assignee:

Concert Pharmaceuticals, Inc., Lexington, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07B 59/00 (2006.01); A61K 31/4184 (2006.01); A61K 31/4985 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/4184 (2013.01); A61K 31/4985 (2013.01); C07B 59/002 (2013.01);
Abstract

This invention in one embodiment is directed to a compound of Formula Ia; where the designation (R) indicates that the designated carbon has the (R) stereochemistry; and wherein Zis hydrogen or fluorine; Zis hydrogen, deuterium, or fluorine; Zis deuterium; Zis fluorine; m is an integer from 0 to 10; n is an integer from 0 to 2; provided that: the sum of m+n does not exceed 10; and when both Zand Zare hydrogen, the sum of m+n is greater than 0, and pharmaceutically acceptable salts thereof. This invention also provides compositions comprising one or more compounds of this invention and a carrier and the use of the disclosed compounds and compositions in methods of treating diseases and conditions that are beneficially treated by administering an antihelminthic agent, such as praziquantel.


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