The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 2018
Filed:
Dec. 03, 2013
Applicant:
Istituto Europeo DE Oncologia S.r.l., Milan, IT;
Inventors:
Mario Varasi, Milan, IT;
Paola Vianello, Milan, IT;
Florian Thaler, Milan, IT;
Paolo Trifiro′, Milan, IT;
Ciro Mercurio, Milan, IT;
Giuseppe Meroni, Milan, IT;
Assignee:
Istituto Europeo di Oncologia S.r.l., Milan, IT;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 211/40 (2006.01); A61K 31/4025 (2006.01); A61K 31/404 (2006.01); A61K 31/4164 (2006.01); A61K 31/496 (2006.01); C07D 215/12 (2006.01); C07D 295/195 (2006.01); C07D 207/50 (2006.01); C07D 213/61 (2006.01); C07D 311/70 (2006.01); C07D 211/58 (2006.01); C07D 263/04 (2006.01); C07D 233/02 (2006.01); C07D 271/113 (2006.01); C07C 209/00 (2006.01); C07C 231/12 (2006.01); C07C 269/06 (2006.01); C07C 303/36 (2006.01); C07D 319/16 (2006.01); C07D 233/32 (2006.01); C07D 239/42 (2006.01); C07D 249/06 (2006.01); C07D 263/22 (2006.01); C07D 271/10 (2006.01); C07D 295/155 (2006.01); C07D 213/64 (2006.01); C07D 307/54 (2006.01); C07C 271/28 (2006.01); C07C 211/49 (2006.01); C07C 215/42 (2006.01); C07C 217/58 (2006.01); C07C 217/74 (2006.01); C07C 233/44 (2006.01); C07C 233/80 (2006.01); C07C 237/06 (2006.01); C07C 247/16 (2006.01); C07C 311/21 (2006.01);
U.S. Cl.
CPC ...
C07C 211/40 (2013.01); A61K 31/404 (2013.01); A61K 31/4025 (2013.01); A61K 31/4164 (2013.01); A61K 31/496 (2013.01); C07C 209/00 (2013.01); C07C 211/49 (2013.01); C07C 215/42 (2013.01); C07C 217/58 (2013.01); C07C 217/74 (2013.01); C07C 231/12 (2013.01); C07C 233/44 (2013.01); C07C 233/80 (2013.01); C07C 237/06 (2013.01); C07C 247/16 (2013.01); C07C 269/06 (2013.01); C07C 271/28 (2013.01); C07C 303/36 (2013.01); C07C 311/21 (2013.01); C07D 207/50 (2013.01); C07D 211/58 (2013.01); C07D 213/61 (2013.01); C07D 213/64 (2013.01); C07D 215/12 (2013.01); C07D 233/02 (2013.01); C07D 233/32 (2013.01); C07D 239/42 (2013.01); C07D 249/06 (2013.01); C07D 263/04 (2013.01); C07D 263/22 (2013.01); C07D 271/10 (2013.01); C07D 271/113 (2013.01); C07D 295/155 (2013.01); C07D 295/195 (2013.01); C07D 307/54 (2013.01); C07D 311/70 (2013.01); C07D 319/16 (2013.01); C07C 2601/02 (2017.05);
Abstract
The present invention relates to cyclopropyl derivatives of general formula (I), wherein A, R, and Rare as defined in the specification. The present application also relates to pharmaceutical compositions containing such compounds and to their use in therapy.