The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 17, 2018

Filed:

Sep. 29, 2015
Applicants:

Eastern Virginia Medical School, Norfolk, VA (US);

Old Dominion University Research Foundation, Norfolk, VA (US);

Inventors:

Richard Nuccitelli, Norfolk, VA (US);

Stephen J. Beebe, Norfolk, VA (US);

Karl H. Schoenbach, Norfolk, VA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 18/14 (2006.01); A61N 1/20 (2006.01); A61N 1/32 (2006.01);
U.S. Cl.
CPC ...
A61N 1/205 (2013.01); A61N 1/327 (2013.01);
Abstract

Methods for a new, drug-free therapy for treating solid skin tumors through the application of nanosecond pulsed electric fields ('nsPEFs') are provided. In one embodiment of the invention, the cells are melanoma cells, and the applied nsPEFs penetrate into the interior of tumor cells and cause tumor cell nuclei to rapidly shrink and tumor blood flow to stop. This new technique provides a highly localized targeting of tumor cells with only minor effects on overlying skin.


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