The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 17, 2018

Filed:

Nov. 13, 2013
Applicant:

Baylor College of Medicine, Houston, TX (US);

Inventors:

Jin Wang, Sugar Land, TX (US);

Fude Feng, Houston, TX (US);

Assignee:

BAYLOR COLLEGE OF MEDICINE, Houston, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); A61K 47/48 (2006.01); A61K 47/42 (2017.01); A61K 9/00 (2006.01); C12N 15/113 (2010.01); A61K 47/64 (2017.01); A61K 47/69 (2017.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48323 (2013.01); A61K 9/0019 (2013.01); A61K 47/42 (2013.01); A61K 47/6455 (2017.08); A61K 47/6935 (2017.08); C12N 15/113 (2013.01); A61K 48/00 (2013.01); C12N 2310/122 (2013.01); C12N 2310/14 (2013.01); C12N 2310/141 (2013.01); C12N 2310/351 (2013.01); C12N 2310/531 (2013.01); C12N 2320/32 (2013.01);
Abstract

In some embodiments, the present disclosure pertains to compositions for nucleic acid delivery into cells. In some embodiments, the composition comprises: (1) a cationic polymer unit comprising a plurality of polymeric arms, where the plurality of polymeric arms comprise poly(aspartic acid) derivatives; and (2) a nucleic acid associated with the cationic polymer unit. In some embodiments, the cationic polymer unit comprises a linker covalently associated with the plurality of polymeric arms. In some embodiments, the cationic polymer unit has a dendritic shape. In some embodiments, the cationic polymer unit has a star-like shape. In some embodiments, the cationic polymer unit is biodegradable. Further embodiments of the present disclosure pertain to methods of delivering a nucleic acid into cells by introducing into the cells one or more of the compositions of the present disclosure.


Find Patent Forward Citations

Wang, Jin. (2018). Multi-arm biodegradable polymers for nucleic acid delivery (U.S. Patent No. 9943608). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9943608

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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