The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 2018
Filed:
Dec. 02, 2014
Virometix Ag, Schlieren, CH;
Swiss Tropical and Public Health Institute, Basel, CH;
Universität Basel, Basel, CH;
Universität Zürich, Zürich, CH;
Arin Ghasparian, Zürich, CH;
Armando Zuniga, Zürich, CH;
Nina Geib, Zürich, CH;
Marco Tamborini, Muttenz, CH;
Maja Jud, Bottmingen, CH;
Gerd Pluschke, Bad Krozingen, DE;
Aniebrys Marrero Nodarse, Zürich, CH;
John Anthony Robinson, Wermatswil, CH;
UNIVERSITÄT ZÜRICH, Zürich, CH;
SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE, Basel, CH;
VIROMETIX AG, Schlieren, CH;
Abstract
The invention relates to lipopeptides consisting of a peptide chain comprising a parallel coiled-coil domain, a proline-rich peptide antigen, and a lipid moiety, all covalently linked, which aggregate to synthetic virus-like particles. Proline-rich peptide antigens considered contain negatively and positively charged amino acid, and at least 15% of the amino acids are proline. Such synthetic virus-like particles carrying proline-rich antigens derived from pneumococcal proteins are useful as vaccines against infectious diseases caused by Gram-positive bacteria such as