The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 2018
Filed:
Jun. 26, 2014
F.hoffmann-la Roche Ag, Basel, CH;
Genentech, Inc., South San Francisco, CA (US);
Adrian Folkes, Basel, CH;
Stephen Shuttleworth, Basel, CH;
Irina Chuckowree, Basel, CH;
Sally Oxenford, Basel, CH;
Nan Chi Wan, Basel, CH;
Georgette Castanedo, South San Francisco, CA (US);
Richard Goldsmith, South San Francisco, CA (US);
Janet Gunzer-Toste, South San Francisco, CA (US);
Tim Heffron, South San Francisco, CA (US);
Simon Mathieu, South San Francisco, CA (US);
Alan Olivero, South San Francisco, CA (US);
Daniel P. Sutherlin, South San Francisco, CA (US);
Bing-Yan Zhu, South San Francisco, CA (US);
Genentech, Inc., South San Francisco, CA (US);
F. Hoffmann-La Roche AG, , CH;
Abstract
Compounds of Formulae Ia, and stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formula Ia for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.