The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2018
Filed:
Dec. 19, 2013
Applicant:
Caris Science, Inc., Irving, TX (US);
Inventors:
David Spetzler, Paradise Valley, AZ (US);
Valeriy Domenyuk, Tempe, AZ (US);
Tassilo Hornung, Tempe, AZ (US);
Günter Mayer, Bonn, DE;
Michael Famulok, Bonn, DE;
Assignee:
Caris Life Sciences Switzerland Holdings GmbH, Basel, CH;
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); G01N 33/574 (2006.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); C12Q 1/68 (2018.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57488 (2013.01); C12N 15/1048 (2013.01); C12Q 1/6811 (2013.01); C12Q 1/6886 (2013.01); G01N 33/5076 (2013.01); G01N 33/5308 (2013.01);
Abstract
Methods are provided for selecting aptamers that are specific to a target of interest from amongst a library of potential aptamer sequences. Aptamers disclosed can be used to detect and/or characterize biological entities of interest, e.g. microvesicles and/or surface antigens. Further disclosed are biomarkers that can be used for diagnosing different disorders including different types of cancer.