The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2018
Filed:
Nov. 02, 2012
Applicant:
Biodesy, Inc., South San Francisco, CA (US);
Inventors:
Joshua S. Salafsky, San Francisco, CA (US);
Ryan P. McGuinness, Tiburon, CA (US);
Assignee:
Biodesy, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/34 (2006.01); C07K 14/82 (2006.01); C12Q 1/42 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/34 (2013.01); C07K 14/82 (2013.01); C12Q 1/42 (2013.01); G01N 2333/82 (2013.01); G01N 2333/916 (2013.01); G01N 2440/00 (2013.01); G01N 2458/00 (2013.01);
Abstract
Provided herein are compositions and methods for identifying and detecting modulators of Ras protein conformational states through the use of second harmonic generation (SHG) technology. Also provided herein are methods for detecting a conformational changes in the three dimensional structure of a protein bound to a supported lipid bilayer.