The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2018
Filed:
Nov. 23, 2012
Applicant:
Active Motif, Inc., Carlsbad, CA (US);
Inventors:
Joseph Fernandez, Carlsbad, CA (US);
Mary Anne Jelinek, Lake Placid, NY (US);
Brian Stanley Egan, Le Mesa, CA (US);
Assignee:
Active Motif, Inc., Carlsbad, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); C07H 21/00 (2006.01); C40B 50/00 (2006.01); C40B 40/06 (2006.01); C12Q 1/68 (2018.01);
U.S. Cl.
CPC ...
C12N 15/1093 (2013.01); C12Q 1/6804 (2013.01);
Abstract
The invention provides novel methods and materials for genetic and genomic analysis using single or multiplex isolation of protein-associated nucleic acids, including transposase-assisted chromatin immunoprecipitation (TAM-ChIP) and antibody-oligonucleotide proximity ligation. These methods comprise tagging and isolating chromatin or other protein-associated nucleic acids and using antibody-oligonucleotide complexes that recognize the proteins associated with such nucleic acids.