The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2018
Filed:
Dec. 11, 2013
Qiagen Gmbh, Hilden, DE;
Roland Fabis, Leverkusen, DE;
QIAGEN GmbH, Hilden, DE;
Abstract
The present invention provides a cost-efficient method for producing particles having a SiOcontaining surface wherein said method comprises a) providing an aqueous reaction composition comprising i) core particles, ii) an added base, iii) a silicate salt, and iv) a pH modulator wherein the pH value of the reaction composition is above the gelation pH value; b) agitating said reaction composition, wherein the pH modulator decreases the pH value of the reaction composition over time and wherein due to said decrease of the pH value of the reaction composition SiOis deposited onto the core particles, whereby particles are formed which have a diameter of 30 μm or less; and c) obtaining the particles. Furthermore, silica particles having high nucleic acid binding properties are provided.