The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2018
Filed:
Oct. 16, 2013
Applicant:
Yale University, New Haven, CT (US);
Inventors:
Laura E. Niklason, Greenwich, CT (US);
Mahboobe Ghaedi, New Haven, CT (US);
Assignee:
Yale University, New Haven, CT (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); A61K 35/42 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0688 (2013.01); A61K 35/42 (2013.01); C12N 2501/11 (2013.01); C12N 2501/115 (2013.01); C12N 2501/117 (2013.01); C12N 2501/119 (2013.01); C12N 2501/16 (2013.01); C12N 2501/415 (2013.01); C12N 2506/45 (2013.01); C12N 2533/50 (2013.01); C12N 2533/52 (2013.01); C12N 2533/54 (2013.01); C12N 2533/70 (2013.01); C12N 2533/90 (2013.01);
Abstract
The present invention relates to compositions and methods for generating populations of tissue precursor cells from pluripotent cells, and preferably induction of stem cells into definitive endoderm to generate anterior foregut endoderm from pluripotent cells. The anterior foregut endoderm cells can then be differentiated into an alveolar epithelial type II cell.