The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 10, 2018

Filed:

Nov. 04, 2011
Applicants:

Yuanyuan Zhang, Winston Salem, NC (US);

Shay Soker, Greensboro, NC (US);

Anthony Atala, Winston Salem, NC (US);

Aleksander Skardal, Clemmons, NC (US);

Inventors:

Yuanyuan Zhang, Winston Salem, NC (US);

Shay Soker, Greensboro, NC (US);

Anthony Atala, Winston Salem, NC (US);

Aleksander Skardal, Clemmons, NC (US);

Assignee:

Wake Forest University Health Sciences, Winston-Salem, NC (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0671 (2013.01); C12N 5/0068 (2013.01); C12N 2513/00 (2013.01); C12N 2533/54 (2013.01); C12N 2533/80 (2013.01); C12N 2533/90 (2013.01);
Abstract

The present invention relates to compositions and methods for mimicking an in vivo environment for culturing cells in vitro. The in vivo mimicking environment is based on the generation of a tissue-specific extracellular matrix wherein the matrix provides a substrate for which the cultured cell originated from. The tissue-specific extracellular matrix can further comprise a component of a whole tissue-specific homogenate.


Find Patent Forward Citations

Loading…