The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2018
Filed:
Jul. 08, 2015
Applicant:
Tdw Group, Grand Cayman, KY;
Inventors:
Assignee:
TDW Group, Grand Cayman, KY;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/573 (2006.01); C07K 16/40 (2006.01); A61K 38/50 (2006.01); C12N 9/78 (2006.01); G01N 33/574 (2006.01); A61K 38/45 (2006.01); A61K 38/51 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A61K 38/45 (2013.01); A61K 38/50 (2013.01); A61K 38/51 (2013.01); C12N 9/78 (2013.01); C12Y 207/00 (2013.01); C12Y 207/03003 (2013.01); C12Y 401/01019 (2013.01); G01N 33/573 (2013.01); G01N 33/57496 (2013.01); C07K 2317/20 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C12Y 305/03006 (2013.01); G01N 2333/9015 (2013.01); G01N 2800/52 (2013.01);
Abstract
Antibodies, and antigen-binding fragments, which specifically bind to argininosuccinate synthase, and related compositions, kits, and methods of use, which are useful as companion diagnostics to identify suitable subjects for arginine deprivation or depletion therapies such as ADI-PEG 20 and other arginine deiminase (ADI) polypeptide-based therapies.