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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9938350 B1

PDFFull Text
Date of Patent:
Apr. 10, 2018

Filed:

Dec. 17, 2015

Receptor tyrosine kinase-like orphan receptor 1 (ror1) single chain fv antibody fragment conjugates and methods of use thereof

Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Thomas J. Kipps, Rancho Santa Fe, CA (US);

Jianqianq Yu, San Diego, CA (US);

Assignee:

The Regents Of The University Of California, Oakland, CA (US);

Attorney:

Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.

Primary Examiner:

Ruixiang Li

Int. Cl.
CPC ...
C07K 16/30 (2006.01); C07K 16/40 (2006.01); C07K 16/46 (2006.01); C07K 14/725 (2006.01); C07K 14/705 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); C07K 14/7051 (2013.01); C07K 14/70521 (2013.01); C07K 16/40 (2013.01); C07K 16/46 (2013.01); C07K 16/468 (2013.01); G01N 33/57492 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/622 (2013.01); C07K 2319/00 (2013.01); C07K 2319/33 (2013.01); G01N 2333/705 (2013.01);
Abstract

Compositions including an antibody single-chain variable fragment (scFv) conjugate that specifically binds to ROR1 tumor-associated antigen are provided. The anti-ROR1 scFv antibody and conjugates may include a biologically-active molecule. Such conjugates may comprise a chimeric receptor to direct T cells to respond to ROR1 cancer cells, Methods to use the scFV conjugates to target cells expressing ROR1 for therapeutic and diagnostic purposes are also provided.

Find Patent Forward Citations

Kipps, Thomas. (2018). Receptor tyrosine kinase-like orphan receptor 1 (ror1) single chain fv antibody fragment conjugates and methods of use thereof (U.S. Patent No. 9938350). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9938350

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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