logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9938331 B1

PDFFull Text
Date of Patent:
Apr. 10, 2018

Filed:

Dec. 16, 2015

Biologically active proteins having increased in vivo and/or in vitro stability

Applicant:

Amunix Operating Inc., Mountain View, CA (US);

Inventors:

Volker Schellenberger, Palo Alto, CA (US);

Willem P. Stemmer, Los Gatos, CA (US);

Chia-Wei Wang, Santa Clara, CA (US);

Michael D. Scholle, Mountain View, CA (US);

Nathaniel C. Gordon, Campbell, CA (US);

Andreas Crameri, Los Altos Hills, CA (US);

Mikhail Popkov, San Diego, CA (US);

Assignee:

Amunix Operating Inc., Mountain View, CA (US);

Attorney:

Wilson Sonsini Goodrich & Rosati

Primary Examiner:

Shulamith H Shafer

Int. Cl.
CPC ...
C07K 1/00 (2006.01); A61K 38/24 (2006.01); C07K 14/00 (2006.01); C07K 14/56 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 14/415 (2006.01); C12N 15/10 (2006.01); G01N 33/68 (2006.01); C07K 14/47 (2006.01); C07K 14/53 (2006.01); C07K 14/61 (2006.01); C07K 14/535 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/56 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); C07K 14/001 (2013.01); C07K 14/415 (2013.01); C07K 14/47 (2013.01); C07K 14/53 (2013.01); C07K 14/535 (2013.01); C07K 14/61 (2013.01); C12N 15/1044 (2013.01); G01N 33/6845 (2013.01); A61K 38/00 (2013.01); C07K 2319/31 (2013.01); C07K 2319/35 (2013.01);
Abstract

The present invention provides unstructured recombinant polymers (URPs) and proteins containing one or more of the URPs. The present invention also provides microproteins, toxins and other related proteinaceous entities, as well as genetic packages displaying these entities. The present invention also provides recombinant polypeptides including vectors encoding the subject proteinaceous entities, as well as host cells comprising the vectors. The subject compositions have a variety of utilities including a range of pharmaceutical applications.

Find Patent Forward Citations

Loading…