The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2018
Filed:
Aug. 27, 2014
Applicant:
Yeda Research and Development Co. Ltd., Rehovot, IL;
Inventors:
Steven J. D. Karlish, Rehovot, IL;
Adriana Katz, Rehovot, IL;
Daniel M. Tal, Rehovot, IL;
Arie Marcovich, Rehovot, IL;
Assignee:
Yeda Research and Development Co. Ltd., Rehovot, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07J 43/00 (2006.01); C07J 19/00 (2006.01);
U.S. Cl.
CPC ...
C07J 43/003 (2013.01); C07J 19/005 (2013.01);
Abstract
The present invention relates to digoxin and digitoxin derivatives that are selective inhibitors of the α2 isoform of Na,K-ATPase, and that reduce intra-ocular pressure. The invention further relates to uses of these derivatives for treating disorders associated with elevated intraocular pressure, such as glaucomas, and/or as cardiotonic agents.