The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 10, 2018

Filed:

Mar. 16, 2015
Applicant:

Guangdong Zhongsheng Pharmaceutical Co., Ltd, Dongguan, Guangdong, CN;

Inventors:

Hao Wu, Shanghai, CN;

Chaofeng Long, Dongguan, CN;

Jun Lin, Shanghai, CN;

Xiaoxin Chen, Dongguan, CN;

Yunhui Li, Shanghai, CN;

Zhuowei Liu, Dongguan, CN;

Changqing Wei, Shanghai, CN;

Lijuan Chen, Dongguan, CN;

Shuhui Chen, Shanghai, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/10 (2006.01); C07D 413/14 (2006.01); C07D 403/10 (2006.01); C07D 403/14 (2006.01); C07D 498/04 (2006.01); C07D 401/10 (2006.01); C07D 491/08 (2006.01); C07D 487/04 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 487/08 (2006.01); C07D 487/10 (2006.01); C07D 471/10 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); C07D 401/10 (2013.01); C07D 413/10 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 471/10 (2013.01); C07D 487/04 (2013.01); C07D 487/08 (2013.01); C07D 487/10 (2013.01); C07D 491/08 (2013.01);
Abstract

Disclosed are quinoline derivatives as hedgehog pathway inhibitors, especially as SMO inhibitors. Compounds of the present invention can be used in treating diseases relating to hedgehog pathway including cancer.


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