The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 10, 2018

Filed:

Mar. 13, 2014
Applicants:

Konstantin Petrukhin, New Windsor, NY (US);

Christopher Cioffi, Albany, NY (US);

Graham Johnson, Sanbornton, NH (US);

Nicoleta Dobri, New York, NY (US);

Emily Freeman, Albany, NY (US);

Ping Chen, Albany, NY (US);

Michael Conlon, Albany, NY (US);

Lei Zhu, Albany, NY (US);

Inventors:

Konstantin Petrukhin, New Windsor, NY (US);

Christopher Cioffi, Albany, NY (US);

Graham Johnson, Sanbornton, NH (US);

Nicoleta Dobri, New York, NY (US);

Emily Freeman, Albany, NY (US);

Ping Chen, Albany, NY (US);

Michael Conlon, Albany, NY (US);

Lei Zhu, Albany, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/04 (2006.01); C07D 213/79 (2006.01); C07D 249/04 (2006.01); C07D 237/28 (2006.01); C07D 471/08 (2006.01); C07D 237/24 (2006.01); C07D 487/04 (2006.01); C07C 233/56 (2006.01); C07D 213/80 (2006.01); C07D 231/56 (2006.01); C07D 239/28 (2006.01); C07D 471/04 (2006.01); C07D 491/052 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); C07C 233/56 (2013.01); C07D 213/79 (2013.01); C07D 213/80 (2013.01); C07D 231/56 (2013.01); C07D 237/24 (2013.01); C07D 239/28 (2013.01); C07D 249/04 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 491/052 (2013.01);
Abstract

The present invention provides a compound having the structure: (structurally represented) wherein R1, R2, R3, R4, and R5 are each independently H, halogen, CF3 or C1-C4 alkyl; R6 is alkyl; A is absent or present, and when present is —C(O)— or —C(O)NH—; B is substituted or unsubstituted monocycle, bicycle, heteromonocycle, heterobicycle, benzyl, CO2H or (C1-C4 alkyl)-CO2H, wherein when B is CO2H, then A is present and is —C(O)—, or a pharmaceutically acceptable salt thereof.


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