The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2018
Filed:
Aug. 06, 2015
Applicant:
Intra-cellular Therapies, Inc., New York, NY (US);
Inventors:
Peng Li, New Milford, NJ (US);
Hailin Zheng, Teaneck, NJ (US);
Jun Zhao, Highland Park, NJ (US);
Lawrence P. Wennogle, Hillsborough, NJ (US);
Assignee:
INTRA-CELLULAR THERAPIES, INC., New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/14 (2006.01);
U.S. Cl.
CPC ...
C07D 487/14 (2013.01);
Abstract
The invention relates to novel inhibitors of phosphodiesterase 1 (PDE1), useful for the treatment of diseases or disorders characterized by disruption of or damage to certain cGMP/PKG mediated pathways (e.g., in cardiac tissue). The invention further relates to pharmaceutical composition comprising the same and methods of treatment of cardiovascular disease and related disorders, e.g., congestive heart disease, atherosclerosis, myocardial infarction, and stroke.