The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2018
Filed:
May. 18, 2015
North China Pharmaceutical Company., Ltd., Shijiazhuang, Hebei, CN;
Zhaozhong Ding, Shanghai, CN;
Guanghua Lai, Shanghai, CN;
Shuhui Chen, Shanghai, CN;
Xiaobing Yan, Shanghai, CN;
North China Pharmaceutical Company., Ltd., Shijiazhuang, CN;
Abstract
Provided is a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein X is selected from a 3-9 membered carbon ring or a ring which is formed by 3-9 membered carbocyclic ring fused with benzo ring, and a 4-10 membered heterocyclic ring or a ring which is formed by 4-10 membered heterocyclic ring fused with benzo ring; Y and Z are independently selected from 4-9 membered saturated heterocyclic rings respectively; Rare independently selected from H, F, Cl, Br, I, CN, OH, SH, NH, CHO, COOH respectively, or selected from the group, optionally substituted by R, consisting of Calkyl, Cheteroalkyl, Ccyclohydrocarbyl, Cheterocyclohydrocarbyl, Calkyl substituted by Ccyclohydrocarbyl or Cheterocyclohydrocarbyl, and Cheteroalkyl substituted by Ccyclohydrocarbyl or Cheterocyclohydrocarbyl. The compound can be used as an anticoagulant for treating and preventing thrombotic disorders, and can meet the real needs of selectivity and a potent inhibitor for coagulation Xa.