The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2018
Filed:
Dec. 02, 2009
Applicants:
Yufang Xiao, Lexington, MA (US);
Bayard R. Huck, Sudbury, MA (US);
Amanda E. Sutton, Hingham, MA (US);
Thomas E. Richardson, Durham, NC (US);
Srinivasa R. Karra, Pembroke, MA (US);
Inventors:
Yufang Xiao, Lexington, MA (US);
Bayard R. Huck, Sudbury, MA (US);
Amanda E. Sutton, Hingham, MA (US);
Thomas E. Richardson, Durham, NC (US);
Srinivasa R. Karra, Pembroke, MA (US);
Assignee:
Merck Patent GmbH, Darmstadt, DE;
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 471/14 (2006.01); C07D 491/147 (2006.01); C07D 495/14 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 471/14 (2013.01); C07D 491/147 (2013.01); C07D 495/14 (2013.01);
Abstract
Disclosed are C-ring modified tricyclic benzonaphthiridinone compounds and analogs thereof, pharmaceutical compositions comprising such compounds and processes for preparing the same. The compounds are useful in the treatment of diseases amenable to protein kinase signal transduction inhibition, regulation and/or modulation.