The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2018
Filed:
Mar. 02, 2015
Guangzhou Magpie Pharmaceutical Co., Ltd., Guangzhou, CN;
Yuqiang Wang, Guangzhou, CN;
Moussa B. H. Youdim, Guangzhou, CN;
Yewei Sun, Guangzhou, CN;
Zaizun Zhang, Guangzhou, CN;
Gaoxiao Zhang, Guangzhou, CN;
Pei Yu, Guangzhou, CN;
Peng Yi, Guangzhou, CN;
Ming Lang, Guangzhou, CN;
Wei Liu, Guangzhou, CN;
Other;
Abstract
The invention generally relates to compounds of formula (I) with neural protective effect, and preparation and uses thereof. The compounds have multiple mechanisms or functions, for example, inhibition of monoamine oxidase and cholinesterase, scavenging of free radicals, and protection of cells such as nerve cells. The compounds can be used for manufacture of medicaments of cell protection, for prevention and/or treatment of monoamine oxidase, cholinesterase and free radicals related diseases, for example, neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and stroke, and free-radical related diseases such as heart disease, myocardial ischemia, diabetes and other cardiovascular and cerebrovascular diseases.