The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 10, 2018

Filed:

Dec. 21, 2015
Applicant:

Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, Baton Rouge, LA (US);

Inventors:

William Hansel, Baton Rouge, LA (US);

Sita Aggarwal, Hammond, LA (US);

Robert P. Hammer, Acton, MA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/64 (2017.01); A61K 47/48 (2006.01); C07K 7/23 (2006.01); A61K 38/24 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48023 (2013.01); A61K 38/24 (2013.01); A61K 47/48246 (2013.01); A61K 47/64 (2017.08); C07K 7/23 (2013.01); A61K 38/00 (2013.01);
Abstract

Conjugating LHRH to(LHRH-) substantially enhances the bioavailability of, targets it to cells expressing LHRH receptors, facilitates intravenous administration, and increases the anti-cancer efficacy of. The conjugate may be used against cancer cells that express the LHRH receptor: pancreas, prostate, breast, testicular, uterine, ovarian, melanoma. LH-conjugates may be used against cancer cells that express the LH receptor: prostate, breast, ovary, testis, uterus, pancreas, and melanoma.


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