The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 10, 2018

Filed:

Dec. 22, 2008
Applicants:

Ricardo Tostes Gazzinelli, Belo Horizonte, BR;

Rafael Polidoro Alves Barbosa, Nova Floresta, BR;

Braulia Costa Caetano, Belo Horizonte, BR;

Alexandre DE Magalhaes Vieira Machado, Belo Horizonte, BR;

Oscar Bruna-romero, Belo Horizonte, BR;

Flavio Fonseca Guimaraes, Belo Horizonte, BR;

Erica Araujo Mendes, Belo Horizonte, BR;

Inventors:

Ricardo Tostes Gazzinelli, Belo Horizonte, BR;

Rafael Polidoro Alves Barbosa, Nova Floresta, BR;

Braulia Costa Caetano, Belo Horizonte, BR;

Alexandre de Magalhaes Vieira Machado, Belo Horizonte, BR;

Oscar Bruna-Romero, Belo Horizonte, BR;

Flavio Fonseca Guimaraes, Belo Horizonte, BR;

Erica Araujo Mendes, Belo Horizonte, BR;

Assignee:

FUNDACAO OSWALDO CRUZ, Rio de Janeiro, BR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/012 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/012 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/545 (2013.01); C12N 2710/24143 (2013.01); C12N 2760/16011 (2013.01);
Abstract

The present invention concerns to recombinant influenza viruses and modified Vaccinia Ankara viruses (MVA), and to a process for construction of recombinant influenza viruses and modified vaccinia Ankara viruses (MVA) with genes that encode for theparasite SAGI (MVA) and SAG2 (MVA and influenza) proteins, by means of a homologous recombination technique between two transfer vectors (for construction of MVA virus) and reverse genetics (for construction of influenza virus). Additionally, the present invention describes a vaccine composition using recombinant influenza viruses and modified vaccinia Ankara viruses (MVA), or recombinant adenoviruses and modified vaccinia Ankara viruses (MVA), for immunization against infections caused by theparasite.


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