The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2018
Filed:
Sep. 02, 2016
Applicant:
Cyvax, Inc., Atlanta, GA (US);
Inventor:
Bira Arya, Ellicott City, MD (US);
Assignee:
Cyvax, Inc., Atlanta, GA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12Q 1/68 (2006.01); C07K 14/435 (2006.01); C07K 14/47 (2006.01); C12N 15/86 (2006.01); A61K 39/00 (2006.01); A61K 39/29 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0007 (2013.01); A61K 39/292 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/53 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55522 (2013.01); A61K 2039/58 (2013.01); A61K 2039/6075 (2013.01); C12N 2730/10143 (2013.01);
Abstract
Disclosed herein are DNA-based vaccines against amyloid β peptide for use in treating and alleviating Alzheimer's Disease and related conditions. A DNA construct comprising DNA encoding one or more amyloid β peptides, such as amino acids 1-11 of Aβ, and DNA encoding a hepatitis B antigens, is administered with an adjuvant or by electroporation. The vaccine can also be formulated using a fusion protein expressed by the disclosed DNA, in combination with an adjuvant.