The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2018
Filed:
Mar. 14, 2013
Applicants:
The University of Chicago, Chicago, IL (US);
John C. Alverdy, Glenview, IL (US);
Inventor:
John C. Alverdy, Glenview, IL (US);
Assignee:
THE UNIVERSITY OF CHICAGO, Chicago, IL (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/765 (2006.01); A61K 33/42 (2006.01); A61K 31/66 (2006.01); A61L 31/02 (2006.01); A61L 31/06 (2006.01); A61L 31/16 (2006.01); A61K 31/77 (2006.01); A61B 17/11 (2006.01);
U.S. Cl.
CPC ...
A61K 31/765 (2013.01); A61K 31/66 (2013.01); A61K 31/77 (2013.01); A61K 33/42 (2013.01); A61L 31/028 (2013.01); A61L 31/06 (2013.01); A61L 31/16 (2013.01); A61B 17/11 (2013.01); A61L 2300/112 (2013.01);
Abstract
Materials and methods for preventing and treating anastomotic leaks are disclosed. Data establishes that pathogenic microbes interfere with establishing epithelial cell barriers in anastomoses and, more generally, with the reconnection of any two portions of like or different tissues comprising epithelia. Suitable prophylactic and therapeutic composition comprise, e.g., a phosphorylated high molecular weight polyethylene glycol compound.