The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2018
Filed:
Jan. 19, 2017
Spero Trinem, Inc., Cambridge, MA (US);
Christopher Phillip Locher, Lexington, MA (US);
Youssef Laafiret Bennani, Lorraine, CA;
Anne-Laure Grillot, Milton, MA (US);
Hardwin O'Dowd, Boston, MA (US);
Emanuele Perola, Brookline, MA (US);
Arnaud Le Tiran, Croissy sur Seine, FR;
Paul S. Charifson, Framingham, MA (US);
SPERO TRINEM, INC., Cambridge, MA (US);
Abstract
The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein X and R are as defined herein. The compounds of formula (I) are useful as gyrase and/or topoisomerase IV inhibitors for treating bacterial infections. The compounds of formula (I) either possess a broad range of anti-bacterial activity and advantageous toxicological properties or are prodrugs of compounds having said activity.