The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2018
Filed:
Apr. 10, 2015
Applicant:
Acerta Pharma B.v., Oss, NL;
Inventors:
Raquel Izumi, San Carlos, CA (US);
Francisco Salva, San Francisco, CA (US);
Ahmed Hamdy, Santa Cruz, CA (US);
Assignee:
ACERTA PHARMA B.V., Oss, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4985 (2006.01); A61K 31/454 (2006.01); A61K 31/519 (2006.01); A61K 31/52 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4985 (2013.01); A61K 31/454 (2013.01); A61K 31/519 (2013.01); A61K 31/52 (2013.01);
Abstract
In some embodiments, the present invention relates to novel small molecule inhibitors that block the CXCR4-SDF-1 signaling pathway by directly inhibiting members of the Tec family of kinases, namely Bruton's tyrosine kinase (BTK), and their use in treating diseases in which pathogenesis is mediated by the CXCR4/SDF-1 signaling pathway.