The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 03, 2018

Filed:

Nov. 12, 2014
Applicant:

The Board of Trustees of the Leland Stanford Junior University, Palo Alto, CA (US);

Inventors:

Michele Pamela Calos, Menlo Park, CA (US);

Ruby Yanru Tsai, San Jose, CA (US);

Fangfang Zhu, Palo Alto, CA (US);

Matthew Gamboa, Palo Alto, CA (US);

Alfonso P. Farruggio, McAllen, TX (US);

Simon Hippenmeyer, Menlo Park, CA (US);

Bosiljka Tasic, Seattle, WA (US);

Birgitt Schüle, Sunnyvale, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01);
Abstract

Methods for inserting a polynucleotide sequence into the genome of a human cell are provided. The present methods result in insertion of a polynucleotide sequence of interest into the H11 locus in the genome of a human cell. Also provided are nucleic acids that include sequences for integrating a polynucleotide sequence of interest into the H11 locus in the genome of a human cell. A transgenic human cell including site specific recombination sites at the H11 locus is also disclosed.


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