The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 03, 2018

Filed:

Jan. 22, 2016
Applicant:

The Trustees of Princeton University, Princeton, NJ (US);

Inventors:

Yibin Kang, Princeton, NJ (US);

Guohong Hu, Piscataway, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 31/337 (2006.01); A61K 31/7105 (2006.01); A61K 31/00 (2006.01); C12Q 1/68 (2018.01); A61K 31/704 (2006.01); A61K 45/06 (2006.01); A61K 31/713 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1135 (2013.01); A61K 31/00 (2013.01); A61K 31/337 (2013.01); A61K 31/704 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); A61K 45/06 (2013.01); C12Q 1/6886 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); C12N 2320/30 (2013.01); C12N 2320/31 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/156 (2013.01);
Abstract

The present invention relates generally to methods for identifying cancer patients with a poor prognosis, and to therapeutic modalities for improving prognosis by combating metastasis and abrogating chemoresistance in cancer cells. Embodiments of the present invention provide an objective means of prognostication regarding the long-term outcome of an incident of cancer, breast cancer in particular. Therapeutic modalities include immunotherapy and anti-sense therapy. Prognosis is determined by measuring the number of copies of the metadherin gene in the patient's cells.


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