logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9932479 B1

PDFFull Text
Date of Patent:
Apr. 03, 2018

Filed:

Jul. 29, 2015

Dyes and compositions, and processes for using same in analysis of protein aggregation and other applications

Applicant:

Enzo Biochem, Inc., New York, NY (US);

Inventors:

Wayne Forrest Patton, Dix Hills, NY (US);

Sergiy M. Yarmoluk, Kyiv, UA;

Praveen Pande, Holbrook, NY (US);

Vladyslava Kovalska, Kyiv, UA;

Lijun Dai, Farmingville, NY (US);

Kateryna Volkova, Kyiv, UA;

Jack Coleman, East Northport, NY (US);

Mykhaylo Losytskyy, Kyiv, UA;

Anthony Ludlum, Ypsilanti, MI (US);

Anatoliy Balanda, Kyiv, UA;

Assignee:

Enzo Biochem, Inc., Farmingdale, NY (US);

Attorney:

Paul Diamond, Esq.

Primary Examiner:

Jezia Riley

Int. Cl.
CPC ...
C09B 23/16 (2006.01); C09B 23/14 (2006.01); G01N 33/58 (2006.01); G01N 33/68 (2006.01); C07D 401/12 (2006.01); C09B 23/01 (2006.01); C09B 23/04 (2006.01); C09B 23/06 (2006.01); C09B 23/10 (2006.01); C12Q 1/68 (2018.01);
U.S. Cl.
CPC ...
C09B 23/145 (2013.01); C07D 401/12 (2013.01); C09B 23/0008 (2013.01); C09B 23/0025 (2013.01); C09B 23/0058 (2013.01); C09B 23/0066 (2013.01); C09B 23/04 (2013.01); C09B 23/06 (2013.01); C09B 23/102 (2013.01); C09B 23/141 (2013.01); G01N 33/582 (2013.01); G01N 33/6845 (2013.01); G01N 2458/30 (2013.01); G01N 2800/2821 (2013.01); G01N 2800/2835 (2013.01);
Abstract

Provided are dyes and compositions which are useful in a number of applications, such as the detection and monitoring protein aggregation, kinetic studies of protein aggregation, neurofibrillary plaques analysis, evaluation of protein formulation stability, protein thermal stability shift assay and analysis of molecular chaperone activity. These dyes and compositions are also useful as probes in nucleic acid and protein detection.

Find Patent Forward Citations

Loading…