The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 03, 2018
Filed:
Nov. 25, 2014
Oxford Biotherapeutics Ltd, Abingdon, GB;
Jonathan Alexander Terrett, Sunnyvale, CA (US);
Chetana Rao-Naik, Walnut Creek, CA (US);
Haichun Huang, Fremont, CA (US);
Sarah Pogue, Redwood City, CA (US);
Erika Meaddough, Gilroy, CA (US);
Michelle Kuhne, San Francisco, CA (US);
Chin Pan, Los Altos, CA (US);
Oxford BioTherapeutics Ltd, Abingdon, GB;
Abstract
The invention provides antibodies which bind to the extracellular domain of the Tyrosine-protein kinase transmembrane receptor Matriptase. Nucleic acid molecules encoding the antibodies, expression vectors, host cells and methods for expressing the antibodies are also provided. The antibodies may be used for the treatment of cancer, including gastric cancer, colorectal cancer, prostate cancer, breast cancer, ovarian cancer lung cancer, preferably SCLC, esophageal cancer, head and neck cancer, pancreatic cancer, lymphoma preferably non-Hodgkin's lymphoma and skin cancer.