The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 03, 2018
Filed:
Nov. 05, 2014
Inserm (Institut National DE LA Sante ET DE LA Recherche Medicale), Paris, FR;
Centre National DE LA Recherche Scientifique (Cnrs), Paris, FR;
Universite DE Montpellier, Montpellier, FR;
Universite Paris-sud, Orsay, FR;
Institut Regional Du Cancer DE Montpellier, Montpellier, FR;
Ecole Normale Superieure DE Cachan, Cachan, FR;
INSERM (Institut National de la Sante et de la Recherche Medicale, Paris, FR;
Centre National de la Recherche Scientifique (CNRS), Paris, FR;
Universite de Montpellier, Montpellier, FR;
Universite Paris- Sud, Orsay, FR;
Institut Regional du Cancer du Montpellier, Montpellier, FR;
Ecole Normale Superieure de Cachan, Cachan, FR;
Abstract
The invention relates to human neutralizing anti-KIT antibodies and uses thereof. More particularly, the invention relates to an antibody comprising a heavy chain variable region comprising SEQ ID NO: 2 in the H-CDR1 region, SEQ ID NO: 3 in the H-CDR2 region and SEQ ID NO: 4 in the H-CDR3 region; and a light chain variable region comprising SEQ ID NO: 6 in the L-CDR1 region, SEQ ID NO: 7 in the L-CDR2 region and SEQ ID NO: 8 in the L-CDR3 region. The invention also relates to an antibody comprising a heavy chain variable region comprising SEQ ID NO: 10 in the H-CDR1 region, SEQ ID NO: 11 in the H-CDR2 region and SEQ ID NO: 12 in the H-CDR3 region; and a light chain variable region comprising SEQ ID NO: 14 in the L-CDR1 region, SEQ ID NO: 15 in the L-CDR2 region and SEQ ID NO: 16 in the L-CDR3 region.