The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 03, 2018

Filed:

Aug. 24, 2017
Applicant:

Innovative Cellular Therapeutics Co., Ltd., Shanghai, CN;

Inventors:

Lei Xiao, Shanghai, CN;

Zhao Wu, Shanghai, CN;

Chengfei Pu, Shanghai, CN;

Zhiyuan Cao, Shanghai, CN;

He Sun, Shanghai, CN;

Mao Bi, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 14/725 (2006.01); A61K 39/395 (2006.01); A61K 38/17 (2006.01); C12N 5/0783 (2010.01); A61K 35/17 (2015.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2896 (2013.01); A61K 35/17 (2013.01); A61K 38/1774 (2013.01); A61K 39/39558 (2013.01); C07K 14/7051 (2013.01); C12N 5/0636 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/585 (2013.01); C12N 7/00 (2013.01); C12N 2501/515 (2013.01);
Abstract

The present disclosure relates to compositions and methods for compositions, methods, and kits for treating cancer using chimeric antigen receptor (CAR) modified cells. Some embodiments of the present disclosure relate to an isolated nucleic acid sequence encoding CAR. The CAR may include an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain. The antigen binding domain may bind to an antigen of a non-essential organ.


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