The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 03, 2018

Filed:

Apr. 16, 2014
Applicant:

Council of Scientific and Industrial Research, Anusandhan Bhawan, Rafi Marg, New Delhi, IN;

Inventors:

Ram A. Vishwakarma, Jammu, IN;

Sandip B. Bharate, Jammu, IN;

Shashi Bhushan, Jammu, IN;

Dilip M. Mondhe, Jammu, IN;

Shreyans K. Jain, Jammu, IN;

Samdarshi Meena, Jammu, IN;

Santosh K. Guru, Jammu, IN;

Anup S. Pathania, Jammu, IN;

Suresh Kumar, Jammu, IN;

Akanksha Behl, Jammu, IN;

Mubashir J. Mintoo, Jammu, IN;

Sonali S. Bharate, Jammu, IN;

Prashant Joshi, Jammu, IN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/04 (2006.01); A61K 31/453 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
C07D 405/04 (2013.01); C07D 405/14 (2013.01);
Abstract

The present invention relates to the rohitukine (5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-4H-chromen-4-ones) analogs of formula A and pharmaceutically acceptable salts thereof. In addition, the invention relates to pharmaceutically acceptable compositions comprising at least one such compound, and methods of using the compounds for treating or preventing various proliferative disorders such as melanoma, leukemia, breast cancer and prostate cancer etc. [insert Formula A here] wherein, n=0 or 1, when n=1, the dotted line indicates the double bond.


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