The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 03, 2018

Filed:

Jul. 21, 2016
Applicant:

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Bertal Huseyin Aktas, Newton, MA (US);

José A. Halperin, Brookline, MA (US);

Michael Chorev, Chestnut Hill, MA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); C07C 275/30 (2006.01); A61K 31/5377 (2006.01); C07D 213/75 (2006.01); C07D 249/14 (2006.01); C07C 275/34 (2006.01); C07C 275/38 (2006.01); C07C 275/40 (2006.01); C07D 213/81 (2006.01); C07D 215/06 (2006.01); C07D 231/56 (2006.01); C07D 233/36 (2006.01); C07D 237/30 (2006.01); C07D 239/34 (2006.01); C07D 239/42 (2006.01); C07D 261/14 (2006.01); C07D 271/12 (2006.01); C07D 277/18 (2006.01); C07D 277/66 (2006.01); C07D 285/14 (2006.01); C07D 295/088 (2006.01); C07D 295/135 (2006.01); C07D 295/192 (2006.01); C07D 307/88 (2006.01); C07D 317/66 (2006.01); C07D 319/08 (2006.01); C07D 333/20 (2006.01); C07D 333/38 (2006.01); C07D 405/12 (2006.01); C07D 409/04 (2006.01);
U.S. Cl.
CPC ...
C07C 275/30 (2013.01); A61K 31/5377 (2013.01); C07C 275/34 (2013.01); C07C 275/38 (2013.01); C07C 275/40 (2013.01); C07D 213/75 (2013.01); C07D 213/81 (2013.01); C07D 215/06 (2013.01); C07D 231/56 (2013.01); C07D 233/36 (2013.01); C07D 237/30 (2013.01); C07D 239/34 (2013.01); C07D 239/42 (2013.01); C07D 249/14 (2013.01); C07D 261/14 (2013.01); C07D 271/12 (2013.01); C07D 277/18 (2013.01); C07D 277/66 (2013.01); C07D 285/14 (2013.01); C07D 295/088 (2013.01); C07D 295/135 (2013.01); C07D 295/192 (2013.01); C07D 307/88 (2013.01); C07D 317/66 (2013.01); C07D 319/08 (2013.01); C07D 333/20 (2013.01); C07D 333/38 (2013.01); C07D 405/12 (2013.01); C07D 409/04 (2013.01); C07C 2601/02 (2017.05); C07C 2602/08 (2017.05);
Abstract

Compositions and methods for inhibiting translation initiation are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, and/or (4) disorders associated with viral infections, using N,N'-diarylureas and/or N,N′-diarylthiourea compounds are described.


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