The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 03, 2018
Filed:
Jul. 24, 2017
Applicant:
University of Georgia Research Foundation, Inc., Athens, GA (US);
Inventors:
Geert-Jan Boons, Athens, GA (US);
Jun Guo, Wuhan, CN;
Xinghai Ning, Watkinsville, GA (US);
Margaretha Wolfert, Athens, GA (US);
Assignee:
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC., Athens, GA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 251/58 (2006.01); A61K 47/54 (2017.01); G01N 33/58 (2006.01); C07C 271/34 (2006.01); A61K 47/61 (2017.01); C07K 14/00 (2006.01); C07K 2/00 (2006.01); C07D 495/04 (2006.01); C07D 311/90 (2006.01); C07D 307/94 (2006.01); C07D 271/12 (2006.01); C07D 261/20 (2006.01); C07D 249/16 (2006.01); C07C 251/44 (2006.01); C07C 211/42 (2006.01); C07C 49/683 (2006.01); C07C 35/37 (2006.01); A61K 49/00 (2006.01); A61K 47/68 (2017.01); C07H 21/00 (2006.01);
U.S. Cl.
CPC ...
C07C 251/58 (2013.01); A61K 47/542 (2017.08); A61K 47/61 (2017.08); A61K 47/6803 (2017.08); A61K 49/0021 (2013.01); A61K 49/0043 (2013.01); A61K 49/0052 (2013.01); C07C 35/37 (2013.01); C07C 49/683 (2013.01); C07C 211/42 (2013.01); C07C 251/44 (2013.01); C07C 271/34 (2013.01); C07D 249/16 (2013.01); C07D 261/20 (2013.01); C07D 271/12 (2013.01); C07D 307/94 (2013.01); C07D 311/90 (2013.01); C07D 495/04 (2013.01); C07H 21/00 (2013.01); C07K 2/00 (2013.01); C07K 14/00 (2013.01); G01N 33/582 (2013.01); C07C 2603/36 (2017.05);
Abstract
1,3-Dipole-functional compounds (e.g., azide functional compounds) can be reacted with certain alkynes in a cyclization reaction to form heterocyclic compounds. Useful alkynes (e.g., strained, cyclic alkynes) and methods of making such alkynes are also disclosed. The reaction of 1,3-dipole-functional compounds with alkynes can be used for a wide variety of applications including the immobilization of biomolecules on a substrate.