The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 03, 2018
Filed:
Nov. 09, 2012
Trustees of Tufts College, Medford, MA (US);
University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Wake Forest University Health Sciences, Winston-Salem, NC (US);
Evangelia Bellas, Somerville, MA (US);
Kacey Marra, Canonsburg, PA (US);
J. Peter Rubin, Pittsburgh, PA (US);
David L. Kaplan, Concord, MA (US);
James J. Yoo, Winston-Salem, NC (US);
Trustees of Tufts College, Medford, MA (US);
University of Pittsburgh of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Wake Forest University Health Sciences, Winston-Salem, NC (US);
Abstract
The inventions provided herein relate to compositions, methods, delivery devices and kits for repairing or augmenting a tissue in a subject. The compositions described herein are injectable such that they can be placed in a tissue to be treated with a minimally-invasive procedure (e.g., by injection) and/or be molded flexibly into a tissue void of any shape and/or size. In some embodiments, the composition described herein comprises a plurality of silk fibroin particles, which can retain their original volume within the tissue for a period of time. The compositions can be used as a filler to replace a tissue void, e.g., for tissue repair and/or augmentation, or as a scaffold to support tissue regeneration and/or reconstruction. In some embodiments, the compositions described herein can be used for soft tissue repair or augmentation.