The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 03, 2018

Filed:

Jun. 13, 2016
Applicants:

Molecular Express, Inc., Rancho Dominguez, CA (US);

The Regents of the University of California, Oakland, CA (US);

Inventors:

Gary Fujii, Rancho Palos Verdes, CA (US);

Francis C. Szoka, Jr., San Francisco, CA (US);

Douglas S. Watson, Harrisonburg, VA (US);

Assignees:

MOLECULAR EXPRESS, INC., Rancho Dominquez, CA (US);

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); C12N 7/00 (2006.01); A61K 47/48 (2006.01); A61K 39/145 (2006.01); A61K 39/385 (2006.01); C07J 9/00 (2006.01); C07J 41/00 (2006.01); C07J 43/00 (2006.01); A61K 39/07 (2006.01); A61K 39/12 (2006.01); A61K 47/54 (2017.01); A61K 47/69 (2017.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48815 (2013.01); A61K 9/1272 (2013.01); A61K 39/07 (2013.01); A61K 39/12 (2013.01); A61K 39/145 (2013.01); A61K 39/385 (2013.01); A61K 47/543 (2017.08); A61K 47/554 (2017.08); A61K 47/6911 (2017.08); A61K 47/6913 (2017.08); C07J 9/00 (2013.01); C07J 41/0055 (2013.01); C07J 43/003 (2013.01); C12N 7/00 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/55572 (2013.01); A61K 2039/60 (2013.01); A61K 2039/6018 (2013.01); A61K 2039/627 (2013.01); C12N 2740/16134 (2013.01); C12N 2760/16134 (2013.01); C12N 2770/00011 (2013.01); C12N 2770/00034 (2013.01);
Abstract

The present invention relates to liposomal vaccine compositions, methods for the manufacture thereof, and methods for the use thereof to stimulate an immune response in an animal. These compositions comprise dimyristoylphosphatidylcholine ('DMPC'); either dimyristoylphosphatidylglycerol ('DMPG') or dimyristoyltrimethylammonium propane (“DMTAP”) or both DMPC and DMTAP; and at least one sterol derivative providing a covalent anchor for one or more immunogenic polypeptide(s) or carbohydrate(s).


Find Patent Forward Citations

Loading…